3D MATRIX [medical technology]

スリー・ディー・マトリックスでご提供させていただいているPuraMatrix™は、米国Shuguang Zhang博士が発明した生体適合性に優れたマテリアルです。このマテリアルに関する論文・資料を、以下に列記(一部抜粋)します。

神経

1.	Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffold. Proceedings of the National Academy of Science (June 2000)
2.	Entrapment of migrating hippocampal neural cells in three-dimensional peptide nanofiber scaffold. Tissue Engineering. 2004 Mar-Apr;10(3-4):643-55.

骨

3.	The enhancement of osteoblast growth and differentiation in vitro on a peptide hydrogel-polyHIPE polymer hybrid material. Biomaterials.2005

軟骨

4.	Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: Implications for cartilage tissue repair. Proceedings of the National Academy of Science (July 2002)
5.	Evaluation of Medium supplemented with Insulin-Transferrin-Selenium for Culture of Primary Bovine Calf Chondrocytes in Three-Dimentional Hydrogel Scaffolds. Tissue Engineering(2005)
6.	Effects of dynamic compressive loading on chondrocyte biosynthesis in self-assembling peptide scaffolds. Journal of Biomechanics (May 2004)

肝臓

7.	Functional differentiation of hepatocyte-like spheroid structures from putative liver progenitor cells in three dimensional peptide scaffolds. Differentiation (Dec 2003)

血管内皮・心臓

8.	Endothelial cells promote cardiac myocyte survival and spatial reorganization: implications for cardiac regeneration.  Circulation. 2004 Aug 24;110(8):962-8.
9.	Injectable Self-Assembling Peptide Nanofibers Create Intramyocardial Microenvironments for Endothelial Cells. Molecular Cardiology(2005)
10.	Self-assembling short oligopeptides and the promotion of angiogenesis. Biomaterials(2005)
11.	The effect of functionalized self-assembling peptide scaffolds on human aortic endothelial cell function. Biomaterials(2005)

総説

12.	Novel peptide-based biomaterial scaffolds for tissue engineering. TRENDS in Biotechnology(janu,2002)
13.	Fabrication of novel biomaterials through molecular self-assembly. Nature biotechnology(oct,2003)
14.	PuraMatrix™:Self-assembling peptide Nanofiber Scaffolds. Zhang et al.