Keiji Nagano

Chairman and Executive Director

After working at ExxonMobil Corporation and then Bain & Company, Nagano started taking part in New Media as the director of New Media Japan Inc. in 2000. While he was vice-president of the Tokyo office of Bain & Co., he also played a key role as the director of the South Korea office for four years in establishing the office. He led projects with clients in various lines of businesses and gained wide experience in communications, high technology, entertainment, and the healthcare businesses at Bain & Co.

Moreover, he supported foreign capital companies to launch businesses in Japan and carried them toward success by understanding them at the operational level on the lines.

He graduated from the Faculty of Technology at the University of Tokyo (chemical engineering) and earned a master’s degree in business economics (MBA) at Columbia University.

Jun Okada

President and Representative Director

He started working as a consultant at the Tokyo office of Bain & Co. in 1998, and was engaged in many projects, including bio investment support for a venture capital company and development support for a pharmaceutical company (as a resident person for a year). In 2005, he started taking charge of the corporate planning of 3-D Matrix and took up the post as director in 2007,and assumed his current position in 2016.

He graduated from the Law Faculty of the University of Tokyo and earned a master’s degree in business economics (MBA) at the INSEAD in France.

Tomoyuki Arai


In 1996, He started working at Pronexus Inc. (specialist of supporting corporate disclosure) and was involved in the tasks of many listed companies and those targeting IPOs. Since 2006, he was engaged in consulting services for IPOs and internal control systems at the CSBA consulting group. In 2007, he became a director of CSBA Investment. Subsequently, he was responsible for achieving the IPO (JASDAQ) for Ascot Corp. in 2008. He started serving in the sections for compliance and corporate planning at 3-D Matrix in 2008 and assumed the post of director in July 2012.

Satoru Kobayashi

Director(Business Development,Japan)

After working at Fresenius medical care, he started working in the Business development at 3-D Matrix in 2007 and assumed his current position in June 2017.

He graduated Hokkaido University Graduate School of Medicine.

Takao Miki

Director(EMEA Business)

Joined Boston Consulting Group (BCG) in 2014 after working at Bain & Company, GE Healthcare Japan.
As a Principal in BCG, he led more than 10 projects in healthcare and manufacturing industries with multinational members. Regarding the healthcare practices, he supported Japanese trading company to build up a medical business in Southeast Asia and led to develop mid-term corporate strategy for a medical device manufacture. In GE Healthcare, he concluded the partnership with Softbank Telecom to start new businesses in the healthcare IT field and achieved a global award.

Received his MBA from Massachusetts Institute of Technology and MS from  the University of Tokyo.

Toshi Amanuma

Director(North America Business)

Toshi started his career at strategy consulting firm Bain & Company, and continued to gain experience at Sony Corporation, 3-D Matrix and JBIC IG Partners. Recently, he served as managing director of 3-D Matrix EMEA, responsible for commercializing 3-D Matrix’s first medical device product across the EMEA region, and as managing director at JBIC IG Partners, a fund GP subsidiary of Japanese government-owned bank JBIC (Japan Bank of International Cooperation), involved in making fund investments and leading fund formation projects. Toshi rejoined 3-D Matrix in August 2019 to lead the US subsidiary, 3-D Matrix, Inc.

Toshi received his MBA from the Tuck School of Business at Dartmouth College, and his MS from Waseda University.

Andy Kim

Executive Officer (Asia Oceania Business)

Andy is equipped with various experience in multinational healthcare companies such as Pfizer, Baxter. Before joining 3-D Matrix in 2016, he worked for Baxter Healthcare as Senior Business Manager Asia-Pacific. He lead significant projects such as conducting market research, developing business roadmaps, and designing and executing brand lifecycle plans, new product launches, and market entrance strategies in partnership with country-level teams in +10 countries across the Asia Pacific. He also specializes in cross-functional online facilitation, profit plans on country/regional base. He earned Master’s degree in Business Administration (MBA) from Georgetown University in Washington, D.C. after bachelor’s degree in Hankuk University of Foreign Studies in Seoul.

Marie Buffier

Executive Officer (R&D, Europe)

She obtained her PhD in Biology, Cancer Research & Endocrinology from the Claude Bernard University of Lyon, France, in 2008. She then worked as a Postdoctoral Research Fellow in USA first at the Medical Center at University of Rochester and then at the New York University Langone Medical Center elucidating the mechanisms of inflammation in the esophageal cancer formation.
She joined 3-D Matrix Europe in 2013 as the Project Manager of External collaboration and set-up multiple collaborations with academics groups and surgeons to expand new applications of 3-D Matrix' peptides technology. She then lead the development of new products in Europe as the Director of Research and Development in 2019 and is holding her current position since 2021.

Lisa Spirio

Executive Officer (R&D, USA)

Lisa conducted research at the Massachusetts Institute of Technology and the University of Utah before joining the founding team at 3-D Matrix when it was originally spun out of MIT.Lisa did her Postdoctoral Fellowships at The Whitehead Institute for Biomedical Research at MIT, where she studied the molecular and cell biological signaling pathways in human breast cancer and at the Department of Oncological Sciences, at the University of Utah, where she identified the genetic basis for an inherited form of colon cancer in humans.During her almost 20 years at 3-D Matrix Lisa managed the US medical device clinical products development strategy via cultivating key partnerships with CRO’s, pharmaceutical and medical device corporations and universities, as well as establishing a strong working relationship with the US FDA. She has secured regulatory acceptance of two Medical Device RFD’s, IDE pilot studies, and three 510(k) clearances to date. Using the 3-D Matrix technology platform, she has developed several pre-clinical models including cell culture, cell therapy and regenerative medicine applications that has led to three patents and provisional patents in process. She has additional background in quality control, clinical-grade GMP production, intellectual property, research partnerships and experience in the dental, cardiac, hemostasis and wound healing markets.

Lisa holds her Ph.D. in Human Genetics from the University of Utah and her B.S. in Biological Sciences from Colorado State University.